Crystal Structure of the Autochaperone Region from the Shigella flexneri Autotransporter IcsA
نویسندگان
چکیده
منابع مشابه
Crystal structure of the autochaperone region from the Shigella flexneri autotransporter IcsA.
The IcsA (intracellular spread gene A) autotransporter from Shigella flexneri is a key virulence factor. We identified a stable fragment comprising residues 591 to 758, which corresponds to the autochaperone region of the IcsA passenger domain. We showed that thermal unfolding of the autochaperone region is reversible and determined its crystal structure at 2.0-Å resolution.
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2011
ISSN: 0021-9193
DOI: 10.1128/jb.00790-10